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Please bear in mind that dogs can drink lots/pee frequently/dribble wee for zillions of reasons, from liver/kidney problems to Cushing's disease, diabetes mellitus, diabetes insipidus, urinary calculi to prostate problems, various other nasties and even simple behavioural issues. I have cases where I have never found an underlying problem. Although obviously all any test can do is show how an organ is functioning there and then, I would be inclined to trust the results. Obviously things can change and any older dog needs to be monitored closely on medication, but he has to be comfortable too. This isn't a personal comment at all Karen, but sometimes owners become so concerned about possible (and pretty unlikely) side effects that they lose sight of the simple fact that their dog is sore. Keep in close touch with the vet, and keep them informed of any other remedies you have tried that have been helpful. :huggles:Tesa said:Even though Max has had test several times giving him the all clear, we can see something is just not quite right with either his kidney's or liver. Have renamed him Piddling Pete :lol: . Am now concerned the Metacam will do more halm than good